EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF POPPY SEEDS IN ZEBRA FISHES

The body's intricate biochemical reaction to damaging stimuli including infection, damage, and poisons is called inflammation. Even though inflammation has a protective function, excessive or persistent inflammation can cause a number of illnesses, such as autoimmune diseases, cardiovascular problems, and arthritis. As a result, the creation of safer and more potent anti-inflammatory drugs has grown in importance within the field of pharmaceutical research. In recent years, zebra fish have emerged as a valuable experimental model for studying inflammation and evaluating anti-inflammatory activity due to their genetic similarity to humans, transparent embryos, rapid development, and cost-effectiveness.
Zebrafish models provide significant advantages in drug screening, toxicity evaluation, and understanding molecular mechanisms involved in inflammation. Their small size and high reproductive capacity enable large-scale screening of potential anti-inflammatory compounds in a short period. Furthermore, the use of zebrafish helps reduce the dependence on higher animal models while maintaining reliable experimental outcomes.